Cardio-metabolic late effects – Yorkshire Specialist Register of Cancer in Children and Young People

The aims of this work are to produce a comprehensive picture of the health profile of children and young people diagnosed with cancer by linking information on patient outcomes from primary care records, secondary care (which will be obtained from Hospital Episode Statistics (HES) data including inpatient, outpatient, A&E and mental health admissions) and other routine datasets. We will endeavour to compare the health of patients on the Register with the background population. Previous work has thoroughly investigated the risk of major cardiovascular outcomes following childhood cancer treatment (using linked-HES data) and we now wish to focus on other areas, including but not limited to mental health, fertility problems, modifiable cardiovascular risk factors and endocrine abnormalities. We hope to identify how these vary by demographic factors as well as type of malignancy and treatment received. Additionally, we hope to establish whether the risks of developing these problems have changed over time as treatment protocols have altered. We will look further at the impact of relapse or poor response to initial treatment on developing these problems.

30/07/2024 (LTHT-University of Leeds)

15/08/2024 – 16/08/2025